Pulse oximetry and methylene blue

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Interference of methylene blue with CO-Oximetry of hemoglobin derivatives.

Methylene blue (MB) is frequently used as an antidote in treating methemoglobinemia (1) because it facilitates the reducing activity of the NADPH-dependent methemoglobin reductase system in erythrocytes (2). However, MB absorbs strongly between 550 and 700 nm (Fig. 1 ), the same spectrophotometric region as that of the various hemoglobin derivatives: oxyhemoglobin (O2Hb), deoxyhemoglobin (HHb),...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 1990

ISSN: 0003-2409,1365-2044

DOI: 10.1111/j.1365-2044.1990.tb14584.x